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THYROID CARCINOMA AT KING EDWARD VIII HOSPITAL, DURBAN, SOUTH AFRICA
Abstract
Background: Western literature depicts papillary carcinoma as the most common thyroid
malignancy foltowed by follicular carcinoma.
Objective: To assess the clinical pattern of Uyroid carcinoma among African and Indian
patients.
Setting: King Edward VIII Hospital, Durban, South Africa.
Design: A retrospective study.
Subjects: One hundred patients with thyroid carcinoma treated at a tertiarj teaching
hospital hctween 1Y'lO and 1997.
Result: Seventj scven patients were Africans and 23 were Indians. The male to female ratio
was L:6. Ninety eight patients presented with goitre with or without regional lymph node
intolvernent or distant disease. The duration of symptoms ranged from one to 360 months.
Thr mean agc at presentation was 48.6t116.0 years. Follicular carcinoma was the most
common malignancy among African patients (68%), followed by papillary carcinoma
( 16 Vr 'r. anaplartic carcinun~ii ( 13 % ) and medullary carcinoma (2.6% 1. Papillary carcinoma
was the n~ust common rnalignat~cy among Indian patients (5770 j rollowed by follicular
carcinoma and mc.dullar> carcinoma. There was no anaptastic carcinoma among Indian
patients. Fifty five patients undemcnt lobectomy with 3Lunder~oingsubsequtnt completion
thyroideclumy. Ninc patients had near total Ihyroidectorny, 27 were offered total
thyroidecton~y as primary surgery and eight had biopsv only. Thc in-hohpital tnortality was
8%. Recurrence ratc was 870.
Conclusion: Most patients present long after the de*rlvprncnt of synlptnms. Follicular
carcinoma is the mast common thyroid malignancy anlong Africans. Further studies are
required to cxplain this phcnommon.
malignancy foltowed by follicular carcinoma.
Objective: To assess the clinical pattern of Uyroid carcinoma among African and Indian
patients.
Setting: King Edward VIII Hospital, Durban, South Africa.
Design: A retrospective study.
Subjects: One hundred patients with thyroid carcinoma treated at a tertiarj teaching
hospital hctween 1Y'lO and 1997.
Result: Seventj scven patients were Africans and 23 were Indians. The male to female ratio
was L:6. Ninety eight patients presented with goitre with or without regional lymph node
intolvernent or distant disease. The duration of symptoms ranged from one to 360 months.
Thr mean agc at presentation was 48.6t116.0 years. Follicular carcinoma was the most
common malignancy among African patients (68%), followed by papillary carcinoma
( 16 Vr 'r. anaplartic carcinun~ii ( 13 % ) and medullary carcinoma (2.6% 1. Papillary carcinoma
was the n~ust common rnalignat~cy among Indian patients (5770 j rollowed by follicular
carcinoma and mc.dullar> carcinoma. There was no anaptastic carcinoma among Indian
patients. Fifty five patients undemcnt lobectomy with 3Lunder~oingsubsequtnt completion
thyroideclumy. Ninc patients had near total Ihyroidectorny, 27 were offered total
thyroidecton~y as primary surgery and eight had biopsv only. Thc in-hohpital tnortality was
8%. Recurrence ratc was 870.
Conclusion: Most patients present long after the de*rlvprncnt of synlptnms. Follicular
carcinoma is the mast common thyroid malignancy anlong Africans. Further studies are
required to cxplain this phcnommon.
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