Open Access
Subscription or Fee Access
CONGENITAL SYPHILIS IN AN IMMUNOCOMPROMISED NEONATE:CASE REPORT
Abstract
SUMMARY
Syphilis is a notifiable and preventable disease, congenital syphilis more so. Consequently,
attention has been recently focused on prenatal diagnosis of foetal syphilis by the use
of ultrasonography apart from the conventional serologic screening. Congenital syphilis
has not been reported from the Kingdom of Lesotho. We report the case of a 3.0kg
male neonate with florid joint and bone lesions of congenital syphilis associated with
HIV infection seen at the Queen Elizabeth II Hospital, Maseru, Kingdom of Lesotho.
Co-existing HIV infection influences the clinical manifestation of syphilis, the progression
of neurosyphilis and the response to standard therapy. The baby had the recommended
standard treatment with good response and he was followed-up for a period of twelve
months with serologic screening and radiographic evaluation.
Syphilis is a notifiable and preventable disease, congenital syphilis more so. Consequently,
attention has been recently focused on prenatal diagnosis of foetal syphilis by the use
of ultrasonography apart from the conventional serologic screening. Congenital syphilis
has not been reported from the Kingdom of Lesotho. We report the case of a 3.0kg
male neonate with florid joint and bone lesions of congenital syphilis associated with
HIV infection seen at the Queen Elizabeth II Hospital, Maseru, Kingdom of Lesotho.
Co-existing HIV infection influences the clinical manifestation of syphilis, the progression
of neurosyphilis and the response to standard therapy. The baby had the recommended
standard treatment with good response and he was followed-up for a period of twelve
months with serologic screening and radiographic evaluation.
Refbacks
- There are currently no refbacks.
