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PRINCIPLES AND PRACTICE OF GAMMA KNIFE RADIOSURGERY: A REVIEW
Abstract
Objectives: To determine the physics, biology, outcomes and risks of gamma knife radiosurgery (GKRS) in treating brain tumours, arteriovenous malformations (AVMs), pain and movement disorders.
Data sources: A retrospective MEDLINE search was used to find all gamma knife radiosurgery studies published from 1967 to 12th March 2005 and strict inclusion criteria were applied.
Study selection: Limited to the review articles in the human study with the key word of gamma knife radiosurgery.
Data extraction: In each subject, both authors reviewed related articles separately.
Data synthesis: Adding up data and compare the results.
Conclusions: The GKRS represents one of the most advanced means available to treat brain tumours, arteriovenous malformations (AVMs), pain and movement disorders safely and effectively. At present, the long-term results after GKRS procedures remain to be documented. The physics, biology, current indications and expected outcomes after GKRS are discussed.
Data sources: A retrospective MEDLINE search was used to find all gamma knife radiosurgery studies published from 1967 to 12th March 2005 and strict inclusion criteria were applied.
Study selection: Limited to the review articles in the human study with the key word of gamma knife radiosurgery.
Data extraction: In each subject, both authors reviewed related articles separately.
Data synthesis: Adding up data and compare the results.
Conclusions: The GKRS represents one of the most advanced means available to treat brain tumours, arteriovenous malformations (AVMs), pain and movement disorders safely and effectively. At present, the long-term results after GKRS procedures remain to be documented. The physics, biology, current indications and expected outcomes after GKRS are discussed.
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