MALIGNANT LYMPHOMA IN WESTERN ETHIOPIA
Abstract
Objective: To identify the pattern of malignant lymphoma in western Ethiopia and compare
it with similar studies conducted in the region.
Design: A retrospective study.
Method: A search was made for all histopathologic diagnosis of malignant lymphoma from
the files of the department for the years 1988-1999. The pathologic diagnosis of Hodgkin's
disease was grouped according to Rye's classification and non-Hodgkin's lymphoma
according to the working formulation for clinical usage classification. The results were
tabulated and analysed.
Setting: The department of pathology of Gondar College of Medical Sciences; the only unit
which provides histopathologic services for the region, that includes Amhara and Tigrai
region.
Subjects: All lymphoma cascs diagnosed at the department were included.
Results: A total of 83 cases of lymphoma were diagnosedl over a period of 11 years (1988-
1999). Their age ranged from four years to 79 years. Twenty one (25.3%) had Hodgkin's
diseases, 61 (73.5%) non Hodgkin's lymphomas and one (11.2%) unspecified lymphoma. The
commonest type of Hodgkin's disease were lymphocyte. predominant (38%) and mixed
cellularity (33.3%). Nodular sclerosing Hodgkin's disease was diagnosed in only one case.
The commonest type of non-Hodgkin's lymphoma was high-grade lymphoma 141.0%)
followed by low grade lymphoma (32.8%). Burkitt's lymp homa was diagnosed in four cases.
The frequency of Hodgkin's disease was high in the firrt and second decades while non-
Hodgkin's lymphoma showed high frequency in the fifth decade.
Conclusion: This study has shown many similarities in proportion of lymphomas and age
and sex distribution of cases. The identified minor dnfferences such as frequencies of
histologic patterns of Hodgkin's disease and paucity of Burkitt's lymphoma deserve
explanation and invites prospective studies.
it with similar studies conducted in the region.
Design: A retrospective study.
Method: A search was made for all histopathologic diagnosis of malignant lymphoma from
the files of the department for the years 1988-1999. The pathologic diagnosis of Hodgkin's
disease was grouped according to Rye's classification and non-Hodgkin's lymphoma
according to the working formulation for clinical usage classification. The results were
tabulated and analysed.
Setting: The department of pathology of Gondar College of Medical Sciences; the only unit
which provides histopathologic services for the region, that includes Amhara and Tigrai
region.
Subjects: All lymphoma cascs diagnosed at the department were included.
Results: A total of 83 cases of lymphoma were diagnosedl over a period of 11 years (1988-
1999). Their age ranged from four years to 79 years. Twenty one (25.3%) had Hodgkin's
diseases, 61 (73.5%) non Hodgkin's lymphomas and one (11.2%) unspecified lymphoma. The
commonest type of Hodgkin's disease were lymphocyte. predominant (38%) and mixed
cellularity (33.3%). Nodular sclerosing Hodgkin's disease was diagnosed in only one case.
The commonest type of non-Hodgkin's lymphoma was high-grade lymphoma 141.0%)
followed by low grade lymphoma (32.8%). Burkitt's lymp homa was diagnosed in four cases.
The frequency of Hodgkin's disease was high in the firrt and second decades while non-
Hodgkin's lymphoma showed high frequency in the fifth decade.
Conclusion: This study has shown many similarities in proportion of lymphomas and age
and sex distribution of cases. The identified minor dnfferences such as frequencies of
histologic patterns of Hodgkin's disease and paucity of Burkitt's lymphoma deserve
explanation and invites prospective studies.
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