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TOXOPLASMA ENCEPHALITIS IN HIV: CASE REPORT
Abstract
InTanzania, nodata are availableon the prevalenceof brain infection by toxoplasma in HIVinfected
patients. A case of a 35-year old n~an with fulminant toxoplmma encephalitis (TE)
is reported for the first tirnc. TE was not suspected clinically in our patient who presented
with a one week history of severe headache and treated empirically with antimalarial drugs.
TE was diagnosed postmortem histologically by haematuxylin-eosin and
imrnunohistochen~ical stain with P30 antibody for toxoplasma antiger. The findings in our
case support the suggestion that a high index of suspicion for TE should be maintained in
HIV-infected patients presenting with focal neurological symptoms, The case highlights the
importance of autvpsy studies in not only documenting a toxoplasma brain lesion but also in
increasing the awareness for its diagnosis in HIV-infected patients in Tanzania and other
developing countries.
patients. A case of a 35-year old n~an with fulminant toxoplmma encephalitis (TE)
is reported for the first tirnc. TE was not suspected clinically in our patient who presented
with a one week history of severe headache and treated empirically with antimalarial drugs.
TE was diagnosed postmortem histologically by haematuxylin-eosin and
imrnunohistochen~ical stain with P30 antibody for toxoplasma antiger. The findings in our
case support the suggestion that a high index of suspicion for TE should be maintained in
HIV-infected patients presenting with focal neurological symptoms, The case highlights the
importance of autvpsy studies in not only documenting a toxoplasma brain lesion but also in
increasing the awareness for its diagnosis in HIV-infected patients in Tanzania and other
developing countries.
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