PREVALENCE AND RISK FACTORS FOR GALL BLADDER POLYPS

Abstract

ABSTRACT
Objective: Polyps of gallbladder are tumour-like lesions of this organ. Little has been known about
factors associated with the occurrence of gallbladder polyps. We aimed to examine prevalence and
factors associated with gallbladder polyps in our region.
Design: Prospective clinical study.
Setting: Kocaeli University Teaching Hospital.
Subjects: Four hundred and thirty two patients were enrolled to the study.
Interventions: Subjects were screened for the presence of any pathological condition for gallbladder
by upper abdominal ultrasonography completed a questionnaire, and underwent a physical
examination and blood chemistry tests.
Results: Family history of gastrointestinal disease, gallbladder disease and any neoplastic disease
and abnormality in HDL-cholesterol levels had most consistent association at univariate analysis.
Multivariate logistic regression analysis showed that family history of any gastrointestinal disease
and abnormalities of HDL-cholesterol levels were significant.
Conclusions: Our findings suggest the formation of gallbladder polyps is associated with fat
metabolism. Other unknown factors may also influence the formation of this lesion. Relationship
between gallbladder polyps and family history of some diseases suggests us to perform some
genetic studies.