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EFFECT OF HELICOBACTER PYLORI INFECTION ON DEEP VEIN THROMBOSIS SEEN IN PATIENTS WITH BEHÇET’S DISEASE

Ö. SENTÜRK, O. ÖZGÜR. O., S. HÜLAGÜ, N.Z. CANTÜRK, A. ÇELEBI, A.T. KARAKAYA

Abstract


Objective: To investigate the role of homocysteine metabolism due to Helicobacter pylori infection on the development of deep vein thrombosis (DVT) in patients with Behcet’s disease (BD).
Design: Prospective clinical study.
Setting: Teaching hospital.
Subject: Fifty-five patients with BD divided into groups, with DVT and without DVT, 19 healthy individuals and 18 patients with coronary artery disease (CAD) were enrolled into the study.
Interventions: Plasma homocysteine and Hp seropositivity were determined.
Results: There was significant Hp positivity in all groups (p > 0.05). Homocysteine levels were not significantly different for each group except patients with CAD (p > 0.05).
Conclusion: There was no difference for frequency of Hp infection in all groups. We conclude that Hp does not influence DVT seen in BD via homocysteine metabolism, but the methinnin-loading test would be appropriate for enlighting patients whose fasting plasma homocysteine levels are found to be normal.

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The East African Medical Journal is published monthly by Kenya Medical Association.

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